Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson
<i>Cnidium monnieri</i> (L.) Cusson (CMC) is a traditional Chinese herbal medicine that has been widely grown and used in Asia. It is also known as “She chuang zi” in China (Chinese: <b>蛇床子</b>), “Jashoshi” in Japan, “Sasangia...
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doaj-0151aae1d4ba4f5aa356efb3fa89fa5e2020-11-25T03:32:38ZengMDPI AGInternational Journal of Molecular Sciences1422-00672020-02-01213100610.3390/ijms21031006ijms21031006Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) CussonYue Sun0Angela Wei Hong Yang1George Binh Lenon2School of Health and Biomedical Sciences, RMIT University, Melbourne 3083, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Melbourne 3083, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Melbourne 3083, Australia<i>Cnidium monnieri</i> (L.) Cusson (CMC) is a traditional Chinese herbal medicine that has been widely grown and used in Asia. It is also known as “She chuang zi” in China (Chinese: <b>蛇床子</b>), “Jashoshi” in Japan, “Sasangia” in Korea, and “Xa sang tu” in Vietnam. This study aimed to provide an up-to-date review of its phytochemistry, ethnopharmacology, pharmacokinetics, and toxicology. All available information on CMC was collected from the Encyclopedia of Traditional Chinese Medicines, PubMed, EMBASE, ScienceDirect, Scopus, Web of Science, and China Network Knowledge Infrastructure. The updated chemical structures of the compounds are those ones without chemical ID numbers or references from the previous review. A total of 429 chemical constituents have been elucidated and 56 chemical structures have been firstly identified in CMC with traceable evidence. They can be categorized as coumarins, volatile constituents, liposoluble compounds, chromones, monoterpenoid glucosides, terpenoids, glycosides, glucides, and other compounds. CMC has demonstrated impressive potential for the management of various diseases in extensive preclinical research. Since most of the studies are overly concentrated on osthole, more research is needed to investigate other chemical constituents.https://www.mdpi.com/1422-0067/21/3/1006she chuang zicnidii fructusherbal medicinenatural productphytotherapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yue Sun Angela Wei Hong Yang George Binh Lenon |
spellingShingle |
Yue Sun Angela Wei Hong Yang George Binh Lenon Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson International Journal of Molecular Sciences she chuang zi cnidii fructus herbal medicine natural product phytotherapy |
author_facet |
Yue Sun Angela Wei Hong Yang George Binh Lenon |
author_sort |
Yue Sun |
title |
Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson |
title_short |
Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson |
title_full |
Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson |
title_fullStr |
Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson |
title_full_unstemmed |
Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of <i>Cnidium monnieri</i> (L.) Cusson |
title_sort |
phytochemistry, ethnopharmacology, pharmacokinetics and toxicology of <i>cnidium monnieri</i> (l.) cusson |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2020-02-01 |
description |
<i>Cnidium monnieri</i> (L.) Cusson (CMC) is a traditional Chinese herbal medicine that has been widely grown and used in Asia. It is also known as “She chuang zi” in China (Chinese: <b>蛇床子</b>), “Jashoshi” in Japan, “Sasangia” in Korea, and “Xa sang tu” in Vietnam. This study aimed to provide an up-to-date review of its phytochemistry, ethnopharmacology, pharmacokinetics, and toxicology. All available information on CMC was collected from the Encyclopedia of Traditional Chinese Medicines, PubMed, EMBASE, ScienceDirect, Scopus, Web of Science, and China Network Knowledge Infrastructure. The updated chemical structures of the compounds are those ones without chemical ID numbers or references from the previous review. A total of 429 chemical constituents have been elucidated and 56 chemical structures have been firstly identified in CMC with traceable evidence. They can be categorized as coumarins, volatile constituents, liposoluble compounds, chromones, monoterpenoid glucosides, terpenoids, glycosides, glucides, and other compounds. CMC has demonstrated impressive potential for the management of various diseases in extensive preclinical research. Since most of the studies are overly concentrated on osthole, more research is needed to investigate other chemical constituents. |
topic |
she chuang zi cnidii fructus herbal medicine natural product phytotherapy |
url |
https://www.mdpi.com/1422-0067/21/3/1006 |
work_keys_str_mv |
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