Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases
Stroke is one of the leading causes of death and disability worldwide. However, treatment options for ischemic stroke remain limited. Matrix-metalloproteinases (MMPs) contribute to brain damage during ischemic strokes by disrupting the blood-brain barrier (BBB) and causing brain edemas. Carnosine, a...
Main Authors: | Eun-Hye Kim, Eun-Sun Kim, Donggeun Shin, Donghyun Kim, Sungbin Choi, Young-Jun Shin, Kyeong-A Kim, Dabi Noh, Ahmet B. Caglayan, G.K. Rajanikant, Arshad Majid, Ok-Nam Bae |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/14/7495 |
Similar Items
-
Expression profiles of carnosine synthesis–related genes in mice after ingestion of carnosine or ß-alanine
by: Miyaji Takayuki, et al.
Published: (2012-04-01) -
CARNOSINE-CONTAINING LIPOSOMES: PREPARATION AND PROPERTIES
by: N. A. Antonova, et al.
Published: (2016-12-01) -
Untersuchungen zur Regulation des Glucosestoffwechsels in
Glioblastomen und dessen Beeinflussung durch Carnosin
by: Oppermann, Henry
Published: (2015) -
Inhibiting Invasion into Human Bladder Carcinoma 5637 Cells with Diallyl Trisulfide by Inhibiting Matrix Metalloproteinase Activities and Tightening Tight Junctions
by: Yung Hyun Choi, et al.
Published: (2013-10-01) -
Effects of carnosine and hypothermia combination therapy on hypoxic-ischemic brain injury in neonatal rats
by: Jun Chul Byun, et al.
Published: (2021-08-01)