Re-Examining the Role of TNF in MS Pathogenesis and Therapy

Re-Examining the Role of TNF in MS Pathogenesis and Therapy

Multiple sclerosis (MS) is a common neurological disorder of putative autoimmune origin. Clinical and experimental studies delineate abnormal expression of specific cytokines over the course of the disease. One major cytokine that has been shown to play a pivotal role in MS is tumor necrosis factor...

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Bibliographic Details
Main Authors: Diego Fresegna, Silvia Bullitta, Alessandra Musella, Francesca Romana Rizzo, Francesca De Vito, Livia Guadalupi, Silvia Caioli, Sara Balletta, Krizia Sanna, Ettore Dolcetti, Valentina Vanni, Antonio Bruno, Fabio Buttari, Mario Stampanoni Bassi, Georgia Mandolesi, Diego Centonze, Antonietta Gentile
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
TNFR1
TNFR2
TNF therapy
demyelination
neurodegeneration
synaptic damage
Online Access:https://www.mdpi.com/2073-4409/9/10/2290

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