Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework

Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework

Elucidation of the chemical structure of natural products constitutes one of the main challenges in Natural Sciences. Here, the authors show that an amino acid-based metal–organic framework exhibits hydrolase-like catalytic activity and crystallographic determination of the resulting products.

Bibliographic Details
Main Authors: Marta Mon, Rosaria Bruno, Sergio Sanz-Navarro, Cristina Negro, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Mario Prejanò, Tiziana Marino, Antonio Leyva-Pérez, Donatella Armentano, Emilio Pardo
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16699-3
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spelling doaj-0177bcbbd0ff4719a8552e4fd92f99f32021-06-20T11:14:07ZengNature Publishing GroupNature Communications2041-17232020-06-011111910.1038/s41467-020-16699-3Hydrolase–like catalysis and structural resolution of natural products by a metal–organic frameworkMarta Mon0Rosaria Bruno1Sergio Sanz-Navarro2Cristina Negro3Jesús Ferrando-Soria4Lucia Bartella5Leonardo Di Donna6Mario Prejanò7Tiziana Marino8Antonio Leyva-Pérez9Donatella Armentano10Emilio Pardo11Instituto de Ciencia Molecular (ICMol), Universidad de ValenciaDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaInstituto de Tecnología Química (UPV–CSIC), Universitat Politècnica de València–Consejo Superior de Investigaciones CientíficasInstituto de Ciencia Molecular (ICMol), Universidad de ValenciaInstituto de Ciencia Molecular (ICMol), Universidad de ValenciaDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaInstituto de Tecnología Química (UPV–CSIC), Universitat Politècnica de València–Consejo Superior de Investigaciones CientíficasDipartimento di Chimica e Tecnologie Chimiche (CTC), Università Della CalabriaInstituto de Ciencia Molecular (ICMol), Universidad de ValenciaElucidation of the chemical structure of natural products constitutes one of the main challenges in Natural Sciences. Here, the authors show that an amino acid-based metal–organic framework exhibits hydrolase-like catalytic activity and crystallographic determination of the resulting products.https://doi.org/10.1038/s41467-020-16699-3
collection DOAJ
language English
format Article
sources DOAJ
author Marta Mon
Rosaria Bruno
Sergio Sanz-Navarro
Cristina Negro
Jesús Ferrando-Soria
Lucia Bartella
Leonardo Di Donna
Mario Prejanò
Tiziana Marino
Antonio Leyva-Pérez
Donatella Armentano
Emilio Pardo
spellingShingle Marta Mon
Rosaria Bruno
Sergio Sanz-Navarro
Cristina Negro
Jesús Ferrando-Soria
Lucia Bartella
Leonardo Di Donna
Mario Prejanò
Tiziana Marino
Antonio Leyva-Pérez
Donatella Armentano
Emilio Pardo
Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
Nature Communications
author_facet Marta Mon
Rosaria Bruno
Sergio Sanz-Navarro
Cristina Negro
Jesús Ferrando-Soria
Lucia Bartella
Leonardo Di Donna
Mario Prejanò
Tiziana Marino
Antonio Leyva-Pérez
Donatella Armentano
Emilio Pardo
author_sort Marta Mon
title Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
title_short Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
title_full Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
title_fullStr Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
title_full_unstemmed Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
title_sort hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-06-01
description Elucidation of the chemical structure of natural products constitutes one of the main challenges in Natural Sciences. Here, the authors show that an amino acid-based metal–organic framework exhibits hydrolase-like catalytic activity and crystallographic determination of the resulting products.
url https://doi.org/10.1038/s41467-020-16699-3
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