Epidemiological, clinical and immunohistochemical aspects of canine lymphoma in the region of Porto Alegre, Brazil

• Main Authors: Elisa B. Neuwald, Luciele V. Teixeira, Francisco O. Conrado, Mariana O.D. da Silva, Nicole R.C. Hlavac, Félix H.D. González
• Format: Article
• Language: English
• Published: Colégio Brasileiro de Patologia Animal (CBPA) 2014-04-01
• Series: Pesquisa Veterinária Brasileira
• Subjects: Linfoma; síndromes paraneoplásicas; sinais clínicos; imuno-histoquímica; caninos
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2014000400009&lng=en&tlng=en

This paper describes the epidemiological, clinical and immunohistochemical characteristics of canine lymphomas diagnosed in the region of Porto Alegre, Brazil. Thirty dogs were enrolled in the study; most of them were male (60%), mixed-breed (23%) and middle-aged or older. The majority (87%) of affected dogs showed the multicentric form. The B-cell phenotype was most frequently detected (62%); 37% of the animals were in clinical stage IV, and 83% were classified as sub-stage "b". Lymphadenopathy was observed in 67% of the cases, and dyspnea, prostration, decreased appetite and vomiting were the most common clinical signs encountered. Anemia was a frequently encountered laboratory alteration (57%), as were leukocytosis (40%), thrombocytopenia (33%), lymphopenia (30%), hyperglobulinemia (20%) and hypercalcemia (13%). The results of this study indicate that the clinical features of dogs with lymphoma in the region of Porto Alegre are similar to those observed worldwide.