Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA[S]

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA[S]

Reverse cholesterol transport (RCT) contributes to the anti-atherogenic effects of HDL. Patients with the orphan disease, familial hypoalphalipoproteinemia (FHA), are characterized by decreased tissue cholesterol removal and an increased atherogenic burden. We performed an open-label uncontrolled pr...

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Bibliographic Details
Main Authors: Ruud S. Kootte, Loek P. Smits, Fleur M. van der Valk, Jean-Louis Dasseux, Constance H. Keyserling, Ronald Barbaras, John F. Paolini, Raul D. Santos, Theo H. van Dijk, Geesje M. Dallinga-van Thie, Aart J. Nederveen, WillemJ.M. Mulder, G.Kees Hovingh, JohnJ.P. Kastelein, Albert K. Groen, ErikS. Stroes
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-I
reverse cholesterol transport
familial hypoalphalipoproteinemia
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752035598X

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