The Multi-Targeting Ligand ST-2223 with Histamine H<sub>3</sub>Receptor and Dopamine D<sub>2</sub>/D<sub>3</sub> Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and BrainOxidative Stress in Mice
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder characterized by social and communicative impairments, as well as repetitive and restricted behaviors (RRBs). With the limited effectiveness of current pharmacotherapies in treating repetitive behaviors, the presen...
Main Authors: | Nermin Eissa, Karthikkumar Venkatachalam, Petrilla Jayaprakash, Markus Falkenstein, Mariam Dubiel, Annika Frank, David Reiner-Link, Holger Stark, Bassem Sadek |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/4/1947 |
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