Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization.

Mendelian randomization (MR) has been used to estimate the causal effect of body mass index (BMI) on particular traits thought to be affected by BMI. However, BMI may also be a modifiable, causal risk factor for outcomes where there is no prior reason to suggest that a causal effect exists. We perfo...

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Bibliographic Details
Main Authors: Louise A C Millard, Neil M Davies, Kate Tilling, Tom R Gaunt, George Davey Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007951