744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy

Bibliographic Details
Main Authors: Feng Wang, Wei Wang, Michael Green, Ruiping Wang, Jianhua Zhang, Andrew Futreal, Jing Ning, James Allison, Padmanee Sharma, Marina Konopleva, Latasha Little, Hussein Abbas, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick Reville, Zoe Alaniz, Gheath Al-Atrash, Koichi Takahashi, Maomao Ding, Jairo Matthews, Sreyashi Basu, Guillermo Garcia-Manero, Steven Kornblau, Kunal Rai, Naval Daver
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:Journal for ImmunoTherapy of Cancer
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spelling doaj-01c9173f79124520a0e23fa07c19006c2020-12-11T10:03:47ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262020-11-018Suppl 310.1136/jitc-2020-SITC2020.0744744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapyFeng Wang0Wei Wang1Michael Green2Ruiping Wang3Jianhua Zhang4Andrew Futreal5Jing Ning6James Allison7Padmanee Sharma8Marina Konopleva9Latasha Little10Hussein Abbas11Katarzyna Tomczak12Praveen Barrodia13Jin Seon Im14Patrick Reville15Zoe Alaniz16Gheath Al-Atrash17Koichi Takahashi18Maomao Ding19Jairo Matthews20Sreyashi Basu21Guillermo Garcia-Manero22Steven Kornblau23Kunal Rai24Naval Daver25The University of Texas MD Anderson Cancer Center, Houston, TX, USADepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaThe University of Texas MD Anderson Cancer Center, Houston, TX, USAGeneral office, Songjiang Center for Disease Control and Prevention, Shanghai, China1 Genomic Medicine, UT MDACC, Houston, Texas, USA 1 Genomic Medicine, UT MDACC, Houston, Texas, USA 3 Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Aff2 grid.240145.60000000122914776MD Anderson Cancer Center Houston TX USA Aff4 grid.240145.60000000122914776MD Anderson Cancer Center Houston TX USA Aff2 0000 0001 2291 4776grid.240145.6Department of LeukemiaUniversity of Texas MD Anderson Cancer Center Houston TX USA Aff1 grid.240145.60000000122914776The University of Texas MD Anderson Cancer Center Houston TX USA The University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USAThe University of Texas MD Anderson Cancer Center, Houston, TX, USA
collection DOAJ
language English
format Article
sources DOAJ
author Feng Wang
Wei Wang
Michael Green
Ruiping Wang
Jianhua Zhang
Andrew Futreal
Jing Ning
James Allison
Padmanee Sharma
Marina Konopleva
Latasha Little
Hussein Abbas
Katarzyna Tomczak
Praveen Barrodia
Jin Seon Im
Patrick Reville
Zoe Alaniz
Gheath Al-Atrash
Koichi Takahashi
Maomao Ding
Jairo Matthews
Sreyashi Basu
Guillermo Garcia-Manero
Steven Kornblau
Kunal Rai
Naval Daver
spellingShingle Feng Wang
Wei Wang
Michael Green
Ruiping Wang
Jianhua Zhang
Andrew Futreal
Jing Ning
James Allison
Padmanee Sharma
Marina Konopleva
Latasha Little
Hussein Abbas
Katarzyna Tomczak
Praveen Barrodia
Jin Seon Im
Patrick Reville
Zoe Alaniz
Gheath Al-Atrash
Koichi Takahashi
Maomao Ding
Jairo Matthews
Sreyashi Basu
Guillermo Garcia-Manero
Steven Kornblau
Kunal Rai
Naval Daver
744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
Journal for ImmunoTherapy of Cancer
author_facet Feng Wang
Wei Wang
Michael Green
Ruiping Wang
Jianhua Zhang
Andrew Futreal
Jing Ning
James Allison
Padmanee Sharma
Marina Konopleva
Latasha Little
Hussein Abbas
Katarzyna Tomczak
Praveen Barrodia
Jin Seon Im
Patrick Reville
Zoe Alaniz
Gheath Al-Atrash
Koichi Takahashi
Maomao Ding
Jairo Matthews
Sreyashi Basu
Guillermo Garcia-Manero
Steven Kornblau
Kunal Rai
Naval Daver
author_sort Feng Wang
title 744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
title_short 744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
title_full 744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
title_fullStr 744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
title_full_unstemmed 744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy
title_sort 744 single cell profiling of acute myeloid leukemia (aml) and its microenvironment reveals a cd8 continuum and adaptable t cell plasticity in response to pd-1 blockade-based therapy
publisher BMJ Publishing Group
series Journal for ImmunoTherapy of Cancer
issn 2051-1426
publishDate 2020-11-01
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