In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid
3D Ti-mesh has been coated with bioceramics under different coating conditions, such as material compositions and micro-porosity, using a dip casting method. Hydroxyapatite (HA), micro-HA particles (HAp), a bioglass (BG) and their different mixtures together with polymer additives were used to contr...
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doaj-01e4bc973429424cbdd5d562605d19412021-05-02T13:25:59ZengTaylor & Francis GroupJournal of Asian Ceramic Societies2187-07642014-09-012321021410.1016/j.jascer.2014.04.002In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluidWei Yi0Xudong Sun1Dun Niu2Xiaozhi Hu3Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education), Northeastern University, Shenyang 110819, ChinaKey Laboratory for Anisotropy and Texture of Materials (Ministry of Education), Northeastern University, Shenyang 110819, ChinaSchool of Science, Northeastern University, Shenyang 110819, ChinaSchool of Mechanical and Chemical Engineering, The University of Western Australia, Perth 6009, Australia3D Ti-mesh has been coated with bioceramics under different coating conditions, such as material compositions and micro-porosity, using a dip casting method. Hydroxyapatite (HA), micro-HA particles (HAp), a bioglass (BG) and their different mixtures together with polymer additives were used to control HA-coating microstructures. Layered composites with the following coating-to-substrate designs, such as BG/Ti, HA + BG/BG/Ti and HAp + BG/BG/Ti, were fabricated. The bioactivity of these coated composites and the uncoated Ti-mesh substrate was then investigated in a simulated body fluid (SBF). The Ti-mesh substrate and BG/Ti composite did not induce biomimetic apatite deposition when they were immersed in SBF for the selected BG, a pressable dental ceramic, used in this study. After seven days in SBF, an apatite layer was formed on both HA + BG/BG/Ti and HAp + BG/BG/Ti composites. The difference is the apatite layer on the HAp + BG/BG/Ti composite was rougher and contained more micro-pores, while the apatite layer on the HA + BG/BG/Ti composite was dense and smooth. The formation of biomimetic apatite, being more bioresorbable, is favored for bone regeneration.http://www.sciencedirect.com/science/article/pii/S2187076414000402HydroxyapatiteBioglassBioactivitySimulated body fluidApatite |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wei Yi Xudong Sun Dun Niu Xiaozhi Hu |
spellingShingle |
Wei Yi Xudong Sun Dun Niu Xiaozhi Hu In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid Journal of Asian Ceramic Societies Hydroxyapatite Bioglass Bioactivity Simulated body fluid Apatite |
author_facet |
Wei Yi Xudong Sun Dun Niu Xiaozhi Hu |
author_sort |
Wei Yi |
title |
In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid |
title_short |
In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid |
title_full |
In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid |
title_fullStr |
In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid |
title_full_unstemmed |
In vitro bioactivity of 3D Ti-mesh with bioceramic coatings in simulated body fluid |
title_sort |
in vitro bioactivity of 3d ti-mesh with bioceramic coatings in simulated body fluid |
publisher |
Taylor & Francis Group |
series |
Journal of Asian Ceramic Societies |
issn |
2187-0764 |
publishDate |
2014-09-01 |
description |
3D Ti-mesh has been coated with bioceramics under different coating conditions, such as material compositions and micro-porosity, using a dip casting method. Hydroxyapatite (HA), micro-HA particles (HAp), a bioglass (BG) and their different mixtures together with polymer additives were used to control HA-coating microstructures. Layered composites with the following coating-to-substrate designs, such as BG/Ti, HA + BG/BG/Ti and HAp + BG/BG/Ti, were fabricated. The bioactivity of these coated composites and the uncoated Ti-mesh substrate was then investigated in a simulated body fluid (SBF). The Ti-mesh substrate and BG/Ti composite did not induce biomimetic apatite deposition when they were immersed in SBF for the selected BG, a pressable dental ceramic, used in this study. After seven days in SBF, an apatite layer was formed on both HA + BG/BG/Ti and HAp + BG/BG/Ti composites. The difference is the apatite layer on the HAp + BG/BG/Ti composite was rougher and contained more micro-pores, while the apatite layer on the HA + BG/BG/Ti composite was dense and smooth. The formation of biomimetic apatite, being more bioresorbable, is favored for bone regeneration. |
topic |
Hydroxyapatite Bioglass Bioactivity Simulated body fluid Apatite |
url |
http://www.sciencedirect.com/science/article/pii/S2187076414000402 |
work_keys_str_mv |
AT weiyi invitrobioactivityof3dtimeshwithbioceramiccoatingsinsimulatedbodyfluid AT xudongsun invitrobioactivityof3dtimeshwithbioceramiccoatingsinsimulatedbodyfluid AT dunniu invitrobioactivityof3dtimeshwithbioceramiccoatingsinsimulatedbodyfluid AT xiaozhihu invitrobioactivityof3dtimeshwithbioceramiccoatingsinsimulatedbodyfluid |
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1721491131245527040 |