Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 Regulation

Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 Regulation

Previously, we established a microRNA (miRNA) expression signature in pancreatic ductal adenocarcinoma (PDAC) tissues using RNA sequencing and found significantly reduced expression of miR-204-5p. Here, we aimed to investigate the functional significance of miR-204-5p and to identify miR-204-5p targ...

Full description

Bibliographic Details
Main Authors: Muhammad Khalid, Tetsuya Idichi, Naohiko Seki, Masumi Wada, Yasutaka Yamada, Haruhi Fukuhisa, Hiroko Toda, Yoshiaki Kita, Yota Kawasaki, Kiyonori Tanoue, Hiroshi Kurahara, Yuko Mataki, Kosei Maemura, Shoji Natsugoe
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
microRNA
miR-204-5p
antitumor
pancreatic ductal adenocarcinoma
pathogenesis
RACGAP1
Online Access:http://www.mdpi.com/2072-6694/11/3/327

Internet

http://www.mdpi.com/2072-6694/11/3/327

Similar Items