Pharmacokinetic Comparison of Berberine in Rat Plasma after Oral Administration of Berberine Hydrochloride in Normal and Post Inflammation Irritable Bowel Syndrome Rats

Pharmacokinetic Comparison of Berberine in Rat Plasma after Oral Administration of Berberine Hydrochloride in Normal and Post Inflammation Irritable Bowel Syndrome Rats

In the present study, post inflammation irritable bowel syndrome (PI-IBS) rats were firstly established by intracolonic instillation of acetic acid with restraint stress. Then the pharmacokinetics of berberine in the rat plasma were compared after oral administration of berberine hydrochloride (25...

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Bibliographic Details
Main Authors: Zipeng Gong, Ying Chen, Ruijie Zhang, Yinghan Wang, Yan Guo, Qing Yang, Haixian Zhang, Yu Dong, Xiaogang Weng, Shuangrong Gao, Xiaoxin Zhu
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:International Journal of Molecular Sciences
Subjects:
berberine
pharmacokinetic
absorption
irritable bowel syndrome
Online Access:http://www.mdpi.com/1422-0067/15/1/456

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