Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry
Background/Aims The national registry for inflammatory bowel disease (IBD) was designed to study epidemiology and prescribing pattern of treatment of IBD in India. Methods A multicenter, cross-sectional, prospective registry was established across four geographical zones of India. Adult patients wit...
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Korean Association for the Study of Intestinal Diseases
2021-04-01
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doaj-0235bc95be3545b6b52bf0223368b12c2021-05-06T05:55:43ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562021-04-0119220621610.5217/ir.2019.09169857Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registryAjit Sood0Kirandeep Kaur1Ramit Mahajan2Vandana Midha3Arshdeep Singh4Sarit Sharma5Amarender Singh Puri6Bhabhadev Goswami7Devendra Desai8C. Ganesh Pai9Kiran Peddi10Mathew Philip11Rakesh Kochhar12Sandeep Nijhawan13Shobna Bhatia14N. Sridhara Rao15 Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Pharmacology, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Internal Medicine, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Community Medicine, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Govind Ballabh Pant Hospital, New Delhi, India Department of Gastroenterology, Gauhati Medical College, Guwahati, India P. D. Hinduja Hospital and Medical Research Centre, Mumbai, India Department of Gastroenterology, Kasturba Medical College, Manipal, India Citizens Centre for Digestive Disorders, Hyderabad, India Lisie Institute of Gastroenterology, Kochi, India Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh, India Department of Gastroenterology, Sawai Man Singh Medical College, Jaipur, India Department of Gastroenterology, King Edward Memorial Hospital, Mumbai, India Purnachandra Gastroenterology Institute, Guntur, IndiaBackground/Aims The national registry for inflammatory bowel disease (IBD) was designed to study epidemiology and prescribing pattern of treatment of IBD in India. Methods A multicenter, cross-sectional, prospective registry was established across four geographical zones of India. Adult patients with ulcerative colitis (UC) or Crohn’s disease (CD) were enrolled between January 2014 and December 2015. Information related to demographics; disease features; complications; and treatment history were collected and analyzed. Results A total of 3,863 patients (mean age, 36.7 ± 13.6 years; 3,232 UC [83.7%] and 631 CD [16.3%]) were enrolled. The majority of patients with UC (n = 1,870, 57.9%) were from north, CD was more common in south (n = 348, 55.5%). The UC:CD ratio was 5.1:1. There was a male predominance (male:female = 1.6:1). The commonest presentation of UC was moderately severe (n = 1,939, 60%) and E2 disease (n = 1,895, 58.6%). Patients with CD most commonly presented with ileocolonic (n = 229, 36.3%) inflammatory (n = 504, 79.9%) disease. Extraintestinal manifestations were recorded among 13% and 20% of patients in UC and CD respectively. Less than 1% patients from both cohorts developed colon cancer (n = 26, 0.7%). The commonly used drugs were 5-aminosalicylates (99%) in both UC and CD followed by azathioprine (34.4%). Biologics were used in only 1.5% of patients; more commonly for UC in north and CD in south. Conclusions The national IBD registry brings out diversities in the 4 geographical zones of India. This will help in aiding research on IBD and improving quality of patient care.http://www.irjournal.org/upload/pdf/ir-2019-09169.pdfinflammatory bowel diseasenational registrycolitis, ulcerativeindiacrohn disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ajit Sood Kirandeep Kaur Ramit Mahajan Vandana Midha Arshdeep Singh Sarit Sharma Amarender Singh Puri Bhabhadev Goswami Devendra Desai C. Ganesh Pai Kiran Peddi Mathew Philip Rakesh Kochhar Sandeep Nijhawan Shobna Bhatia N. Sridhara Rao |
spellingShingle |
Ajit Sood Kirandeep Kaur Ramit Mahajan Vandana Midha Arshdeep Singh Sarit Sharma Amarender Singh Puri Bhabhadev Goswami Devendra Desai C. Ganesh Pai Kiran Peddi Mathew Philip Rakesh Kochhar Sandeep Nijhawan Shobna Bhatia N. Sridhara Rao Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry Intestinal Research inflammatory bowel disease national registry colitis, ulcerative india crohn disease |
author_facet |
Ajit Sood Kirandeep Kaur Ramit Mahajan Vandana Midha Arshdeep Singh Sarit Sharma Amarender Singh Puri Bhabhadev Goswami Devendra Desai C. Ganesh Pai Kiran Peddi Mathew Philip Rakesh Kochhar Sandeep Nijhawan Shobna Bhatia N. Sridhara Rao |
author_sort |
Ajit Sood |
title |
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry |
title_short |
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry |
title_full |
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry |
title_fullStr |
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry |
title_full_unstemmed |
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry |
title_sort |
colitis and crohn’s foundation (india): a first nationwide inflammatory bowel disease registry |
publisher |
Korean Association for the Study of Intestinal Diseases |
series |
Intestinal Research |
issn |
1598-9100 2288-1956 |
publishDate |
2021-04-01 |
description |
Background/Aims The national registry for inflammatory bowel disease (IBD) was designed to study epidemiology and prescribing pattern of treatment of IBD in India. Methods A multicenter, cross-sectional, prospective registry was established across four geographical zones of India. Adult patients with ulcerative colitis (UC) or Crohn’s disease (CD) were enrolled between January 2014 and December 2015. Information related to demographics; disease features; complications; and treatment history were collected and analyzed. Results A total of 3,863 patients (mean age, 36.7 ± 13.6 years; 3,232 UC [83.7%] and 631 CD [16.3%]) were enrolled. The majority of patients with UC (n = 1,870, 57.9%) were from north, CD was more common in south (n = 348, 55.5%). The UC:CD ratio was 5.1:1. There was a male predominance (male:female = 1.6:1). The commonest presentation of UC was moderately severe (n = 1,939, 60%) and E2 disease (n = 1,895, 58.6%). Patients with CD most commonly presented with ileocolonic (n = 229, 36.3%) inflammatory (n = 504, 79.9%) disease. Extraintestinal manifestations were recorded among 13% and 20% of patients in UC and CD respectively. Less than 1% patients from both cohorts developed colon cancer (n = 26, 0.7%). The commonly used drugs were 5-aminosalicylates (99%) in both UC and CD followed by azathioprine (34.4%). Biologics were used in only 1.5% of patients; more commonly for UC in north and CD in south. Conclusions The national IBD registry brings out diversities in the 4 geographical zones of India. This will help in aiding research on IBD and improving quality of patient care. |
topic |
inflammatory bowel disease national registry colitis, ulcerative india crohn disease |
url |
http://www.irjournal.org/upload/pdf/ir-2019-09169.pdf |
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