SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol

SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol

Abstract Background SWI/SNF chromatin remodeling genes are required for normal acute responses to alcohol in C. elegans and are associated with alcohol use disorder in two human populations. In an effort to discover the downstream genes that are mediating this effect, we identified SWI/SNF-regulated...

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Bibliographic Details
Main Authors: Laura D. Mathies, Jonathan H. Lindsay, Amal P. Handal, GinaMari G. Blackwell, Andrew G. Davies, Jill C. Bettinger
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
SWI/SNF chromatin remodeling
Ethanol
Alcohol
C. elegans
Transcriptome
cbp-1
Online Access:http://link.springer.com/article/10.1186/s12864-020-07059-y

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http://link.springer.com/article/10.1186/s12864-020-07059-y

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