Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway
Bixin and norbixin are natural food colourants synthesised from Bixa orellana L seeds. This study explores the mechanism of apocarotenoids (bixin and norbixin) on the aggressive B16 murine melanoma as an anti-cancer agent. The apocarotenoids inhibited the cell viability of B16 melanoma in a time- an...
Main Authors: | Amrita Anantharaman, Hridya Hemachandran, Sankari Mohan, Dhanoop Manikoth Ayyathan, Thirumal Kumar D, George Priya Doss C, Ramamoorthy Siva |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-01-01
|
Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464615005605 |
Similar Items
-
The safety of annatto extracts (E 160b) as a food additive
by: EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
Published: (2016-08-01) -
The Level of SGOT and SGPT after The Administration of Powdered Colorant Pigment Isolated from Kesumba Keling’s (Bixa Orellana) Seed Coats An experimental study in Balb/C Mice
by: Suparmi Suparmi, et al.
Published: (2011-06-01) -
Enriquecimento de norbixina por processos físico-químicos a partir de bixina de sementes de urucum (Bixa orellana L.) e avaliação da atividade antioxidante e antibacteriana in vitro
by: Marina Gagliardo Pires
Published: (2018) -
Enriquecimento de norbixina por processos físico-químicos a partir de bixina de sementes de urucum (Bixa orellana L.) e avaliação da atividade antioxidante e antibacteriana in vitro
by: Pires, Marina Gagliardo
Published: (2018) -
Safety of annatto E and the exposure to the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive
by: EFSA Panel on Food Additives and Flavourings (EFSA FAF Panel), et al.
Published: (2019-03-01)