Clinical and Immunological Characteristics of Acute Tonsillopharyngitis in Children

The article deals with the pressing issues of timely diagnosis of acute tonsillopharyngitis in children. Particular attention is paid to early diagnosis of acute streptococcal tonsillopharyngitis. As additional paraclinical criteria to confirm the streptococcal nature of acute tonsillopharyngitis, t...

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Bibliographic Details
Main Authors: O.K. Koloskova, L.A. Ivanova, O.V. Bielashova, U.I. Marusyk
Format: Article
Language:English
Published: Publishing House Zaslavsky 2015-02-01
Series:Aktualʹnaâ Infektologiâ
Subjects:
Online Access:http://ai.zaslavsky.com.ua/article/view/78506
Description
Summary:The article deals with the pressing issues of timely diagnosis of acute tonsillopharyngitis in children. Particular attention is paid to early diagnosis of acute streptococcal tonsillopharyngitis. As additional paraclinical criteria to confirm the streptococcal nature of acute tonsillopharyngitis, there were selected indicators of cellular immunity (content in peripheral blood of CD3, CD4, CD8, CD22). Sufficient indicators of sensitivity (80 %) and specificity (81.3 %) enable to use integrated clinical and immunological parameters, which include the contents of CD8-lymphocytes > 10 %, CD-3 lymphocytes > 30 %, CD22-lymphocytes < 18 % in the peripheral blood with a total evaluation of the clinical status by McIsaac’s scale ≥ 4 points to confirm the streptococcal nature of acute tonsillopharyngitis in children.
ISSN:2312-413X
2312-4148