Ring finger protein 152-dependent degradation of TSPAN12 suppresses hepatocellular carcinoma progression
Abstract Background Hepatocellular carcinoma (HCC) is the third cause of cancer death in the world, and few molecularly targeted anticancer therapies have been developed to treat it. The E3 ubiquitin ligase RNF152 has been reported to regulate the activity of the mechanistic target of rapamycin comp...
Main Authors: | Jian Wan, Shunfang Liu, Wanju Sun, Haiyi Yu, Wenlian Tang, Wei Liu, Jing Ji, Bin Liu |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-021-01806-1 |
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