When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing

When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing

Here, we sequenced DNA extracted from a necrotic hepatic lesion from a patient with suspected chronic hepatic brucelloma but negative culture results. Although most of the taxonomically classified sequencing reads corresponded to human genome sequences, our data suggest that whole-metagenome shotgun...

Full description

Bibliographic Details
Main Authors: Vladimir Lazarevic, Nadia Gaïa, Myriam Girard, Stefano Leo, Abdessalam Cherkaoui, Gesuele Renzi, Stéphane Emonet, Sharon Jamme, Etienne Ruppé, Sandrine Vijgen, Laura Rubbia-Brandt, Christian Toso, Jacques Schrenzel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
Brucella
liver abscess
clinical metagenomics
molecular diagnosis of infectious diseases
next-generation sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01566/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01566/full

Similar Items