Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study
Based on available evidence, muscle strengthening and cardiovascular exercises can help maintain function and not adversely affect the progression of disease in patients with ALS. However, this evidence is not sufficiently detailed to recommend a specific exercise prescription. The purpose of this p...
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doaj-02ae7cd4d78b4cd9943ff3f0504b1fa12020-11-24T23:20:10ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602018-03-0128110.4081/ejtm.2018.72785622Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled studyAntonio Merico0Marianna Cavinato1Caterina Gregorio2Alessandra Lacatena3Elisabetta Gioia4Francesco Piccione5Corrado Angelini6Neurorehabilitation Department, San Camillo Hospital Foundation, Institute of Care and Research, VeniceNeurorehabilitation Department, San Camillo Hospital Foundation, Institute of Care and Research, VeniceDepartment of Economic, mathematical and statistical sciences, University of TriesteRehabilitation Department, Azienda Sanitaria Locale, TarantoRehabilitation Department, Unità Locale Socio-Sanitaria Serenissima, VeniceNeurorehabilitation Department, San Camillo Hospital Foundation, Institute of Care and Research, VeniceNeurorehabilitation Department, San Camillo Hospital Foundation, Institute of Care and Research, VeniceBased on available evidence, muscle strengthening and cardiovascular exercises can help maintain function and not adversely affect the progression of disease in patients with ALS. However, this evidence is not sufficiently detailed to recommend a specific exercise prescription. The purpose of this project was to assess clinical outcomes of a combined exercise programme to increase knowledge of rehabilitation in ALS patients. 38 ALS patients were assigned randomly to two groups: one group underwent a specific exercise programme (ALS-EP) based on a moderate aerobic workout and isometric contractions, and the second group followed a standard neuromotor rehabilitation treatment. Objective evaluation consisted of cardiovascular measures, muscle strength and fatigue. Some positive effects of physical activity on ALS patients were found. Among the benefits, an overall improvement of functional independence in all patients, independently of the type of exercise conducted was seen. In addition, improvements in muscle power, oxygen consumption and fatigue were specifically observed in the ALS-EP group, all hallmarks of a training effect for the specific exercises. In conclusion, moderate intensity exercise is beneficial in ALS, helping in avoiding deconditioning and muscle atrophy resulting from progressive inactivity.http://www.pagepressjournals.org/index.php/bam/article/view/7278Amyotrophic Lateral Sclerosis, neurorehabilitation, endurance training, isometric exercise |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Antonio Merico Marianna Cavinato Caterina Gregorio Alessandra Lacatena Elisabetta Gioia Francesco Piccione Corrado Angelini |
spellingShingle |
Antonio Merico Marianna Cavinato Caterina Gregorio Alessandra Lacatena Elisabetta Gioia Francesco Piccione Corrado Angelini Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study European Journal of Translational Myology Amyotrophic Lateral Sclerosis, neurorehabilitation, endurance training, isometric exercise |
author_facet |
Antonio Merico Marianna Cavinato Caterina Gregorio Alessandra Lacatena Elisabetta Gioia Francesco Piccione Corrado Angelini |
author_sort |
Antonio Merico |
title |
Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study |
title_short |
Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study |
title_full |
Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study |
title_fullStr |
Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study |
title_full_unstemmed |
Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study |
title_sort |
effects of combined endurance and resistance training in amyotrophic lateral sclerosis: a pilot, randomized, controlled study |
publisher |
PAGEPress Publications |
series |
European Journal of Translational Myology |
issn |
2037-7452 2037-7460 |
publishDate |
2018-03-01 |
description |
Based on available evidence, muscle strengthening and cardiovascular exercises can help maintain function and not adversely affect the progression of disease in patients with ALS. However, this evidence is not sufficiently detailed to recommend a specific exercise prescription. The purpose of this project was to assess clinical outcomes of a combined exercise programme to increase knowledge of rehabilitation in ALS patients. 38 ALS patients were assigned randomly to two groups: one group underwent a specific exercise programme (ALS-EP) based on a moderate aerobic workout and isometric contractions, and the second group followed a standard neuromotor rehabilitation treatment. Objective evaluation consisted of cardiovascular measures, muscle strength and fatigue. Some positive effects of physical activity on ALS patients were found. Among the benefits, an overall improvement of functional independence in all patients, independently of the type of exercise conducted was seen. In addition, improvements in muscle power, oxygen consumption and fatigue were specifically observed in the ALS-EP group, all hallmarks of a training effect for the specific exercises. In conclusion, moderate intensity exercise is beneficial in ALS, helping in avoiding deconditioning and muscle atrophy resulting from progressive inactivity. |
topic |
Amyotrophic Lateral Sclerosis, neurorehabilitation, endurance training, isometric exercise |
url |
http://www.pagepressjournals.org/index.php/bam/article/view/7278 |
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