Toxoplasma F-box protein 1 is required for daughter cell scaffold function during parasite replication.

By binding to the adaptor protein SKP1 and serving as substrate receptors for the SKP1 Cullin, F-box E3 ubiquitin ligase complex, F-box proteins regulate critical cellular processes including cell cycle progression and membrane trafficking. While F-box proteins are conserved throughout eukaryotes an...

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Bibliographic Details
Main Authors: Carlos Gustavo Baptista, Agnieszka Lis, Bowen Deng, Elisabet Gas-Pascual, Ashley Dittmar, Wade Sigurdson, Christopher M West, Ira J Blader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007946

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