Identification of a Neutralizing Monoclonal Antibody that Recognizes a Unique Epitope on Domain III of the Envelope Protein of Tembusu Virus

Identification of a Neutralizing Monoclonal Antibody that Recognizes a Unique Epitope on Domain III of the Envelope Protein of Tembusu Virus

Domain III of the envelope protein (EDIII) is the major target of flavivirus neutralizing antibody. To date, little is known regarding antibody-mediated neutralization of Tembusu virus (TMUV), a novel flavivirus emerging in duck in 2010. Here, a novel monoclonal antibody (MAb), designated 12F11, was...

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Bibliographic Details
Main Authors: Shenghua Qu, Xiaoyan Wang, Lixin Yang, Junfeng Lv, Runze Meng, Weiqian Dai, Qingxiangzi Li, Huicong Liu, Bing Zhang, Dabing Zhang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Viruses
Subjects:
duck
Tembusu virus
monoclonal antibody
neutralizing antibody
antibody-mediated neutralization
epitope
Online Access:https://www.mdpi.com/1999-4915/12/6/647

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