Exposure to Hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

Exposure to Hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharziasis), a disease affecting 67 million people worldwide and causing an important economic burden. The schistosomicides hycanthone, and its later proxy oxamniquine, were widely used for treatments...

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Bibliographic Details
Main Authors: David eRoquis, Julie MJ Lepesant, Emanuel eVillafan, Cristina eVieira, Céline eCosseau, Christoph eGrunau
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
Hycanthone
Oxamniquine
Schistosoma mansoni
epigenetics
Resistance
induction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00207/full

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