Orthopoxvirus DNA in Eurasian Lynx, Sweden
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ra...
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Centers for Disease Control and Prevention
2011-04-01
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doaj-02dea3d5f9ca486d94a4973cfacf0cdd2020-11-25T00:38:18ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592011-04-0117462663210.3201/eid1704.091899Orthopoxvirus DNA in Eurasian Lynx, SwedenMorten TrylandMalachy Ifeanyi OkekeCarl Hård af SegerstadTorsten MörnerTerje TraavikMarie-Pierre Ryser-DegiorgisCowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus.https://wwwnc.cdc.gov/eid/article/17/4/09-1899_articleCowpox virusepidemiologyorthopoxviruswildlifezoonosisviruses |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Morten Tryland Malachy Ifeanyi Okeke Carl Hård af Segerstad Torsten Mörner Terje Traavik Marie-Pierre Ryser-Degiorgis |
spellingShingle |
Morten Tryland Malachy Ifeanyi Okeke Carl Hård af Segerstad Torsten Mörner Terje Traavik Marie-Pierre Ryser-Degiorgis Orthopoxvirus DNA in Eurasian Lynx, Sweden Emerging Infectious Diseases Cowpox virus epidemiology orthopoxvirus wildlife zoonosis viruses |
author_facet |
Morten Tryland Malachy Ifeanyi Okeke Carl Hård af Segerstad Torsten Mörner Terje Traavik Marie-Pierre Ryser-Degiorgis |
author_sort |
Morten Tryland |
title |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_short |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_full |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_fullStr |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_full_unstemmed |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_sort |
orthopoxvirus dna in eurasian lynx, sweden |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2011-04-01 |
description |
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus. |
topic |
Cowpox virus epidemiology orthopoxvirus wildlife zoonosis viruses |
url |
https://wwwnc.cdc.gov/eid/article/17/4/09-1899_article |
work_keys_str_mv |
AT mortentryland orthopoxvirusdnaineurasianlynxsweden AT malachyifeanyiokeke orthopoxvirusdnaineurasianlynxsweden AT carlhardafsegerstad orthopoxvirusdnaineurasianlynxsweden AT torstenmorner orthopoxvirusdnaineurasianlynxsweden AT terjetraavik orthopoxvirusdnaineurasianlynxsweden AT mariepierreryserdegiorgis orthopoxvirusdnaineurasianlynxsweden |
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1725297933424787456 |