Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata
Benign so-called “brown tumors” secondary to hyperparathyroidism are a rare diagnostic pitfall due to their impressively malignant-like character in various imaging modalities. We present the case of a 65-year-old male patient with multiple unclear osteolytic lesions on prior imaging suspicious for...
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MDPI AG
2021-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/8/1355 |
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doaj-02e457dc1b7d485ebf5e704a47c7df3c2021-08-26T13:40:02ZengMDPI AGDiagnostics2075-44182021-07-01111355135510.3390/diagnostics11081355Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica GeneralisataAdrien Holzgreve0Matthias P. Fabritius1Thomas Knösel2Lena M. Mittlmeier3Johannes Rübenthaler4Reinhold Tiling5Christoph J. Auernhammer6Peter Bartenstein7Marcus Unterrainer8Department of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, GermanyInstitute of Pathology, Faculty of Medicine, LMU Munich, 81377 Munich, GermanyDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Medicine IV, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, GermanyBenign so-called “brown tumors” secondary to hyperparathyroidism are a rare diagnostic pitfall due to their impressively malignant-like character in various imaging modalities. We present the case of a 65-year-old male patient with multiple unclear osteolytic lesions on prior imaging suspicious for metastatic malignant disease. Eventually, findings of <sup>18</sup>F-FDG PET/CT staging and <sup>99m</sup>Tc-MIBI scintigraphy resulted in revision of the initially suspected malignant diagnosis. This case illustrates how molecular imaging findings non-invasively corroborate the correct diagnosis of osteitis fibrosa cystica generalisata with the formation of multiple benign brown tumors.https://www.mdpi.com/2075-4418/11/8/1355<sup>18</sup>F-FDG PET/CT<sup>99m</sup>Tc-MIBI SPECT/CTpitfallosteitis fibrosa cystica generalisatabrown tumorparathyroid adenoma |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Adrien Holzgreve Matthias P. Fabritius Thomas Knösel Lena M. Mittlmeier Johannes Rübenthaler Reinhold Tiling Christoph J. Auernhammer Peter Bartenstein Marcus Unterrainer |
| spellingShingle |
Adrien Holzgreve Matthias P. Fabritius Thomas Knösel Lena M. Mittlmeier Johannes Rübenthaler Reinhold Tiling Christoph J. Auernhammer Peter Bartenstein Marcus Unterrainer Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata Diagnostics <sup>18</sup>F-FDG PET/CT <sup>99m</sup>Tc-MIBI SPECT/CT pitfall osteitis fibrosa cystica generalisata brown tumor parathyroid adenoma |
| author_facet |
Adrien Holzgreve Matthias P. Fabritius Thomas Knösel Lena M. Mittlmeier Johannes Rübenthaler Reinhold Tiling Christoph J. Auernhammer Peter Bartenstein Marcus Unterrainer |
| author_sort |
Adrien Holzgreve |
| title |
Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata |
| title_short |
Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata |
| title_full |
Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata |
| title_fullStr |
Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata |
| title_full_unstemmed |
Molecular Imaging with <sup>18</sup>F-FDG PET/CT and <sup>99m</sup>Tc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata |
| title_sort |
molecular imaging with <sup>18</sup>f-fdg pet/ct and <sup>99m</sup>tc-mibi spect/ct in osteitis fibrosa cystica generalisata |
| publisher |
MDPI AG |
| series |
Diagnostics |
| issn |
2075-4418 |
| publishDate |
2021-07-01 |
| description |
Benign so-called “brown tumors” secondary to hyperparathyroidism are a rare diagnostic pitfall due to their impressively malignant-like character in various imaging modalities. We present the case of a 65-year-old male patient with multiple unclear osteolytic lesions on prior imaging suspicious for metastatic malignant disease. Eventually, findings of <sup>18</sup>F-FDG PET/CT staging and <sup>99m</sup>Tc-MIBI scintigraphy resulted in revision of the initially suspected malignant diagnosis. This case illustrates how molecular imaging findings non-invasively corroborate the correct diagnosis of osteitis fibrosa cystica generalisata with the formation of multiple benign brown tumors. |
| topic |
<sup>18</sup>F-FDG PET/CT <sup>99m</sup>Tc-MIBI SPECT/CT pitfall osteitis fibrosa cystica generalisata brown tumor parathyroid adenoma |
| url |
https://www.mdpi.com/2075-4418/11/8/1355 |
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