T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent in vitro
The production of antibody-secreting plasma cells and memory B cells requires the interaction of T follicular helper (Tfh) cells with B cells in the follicle and is modulated by T follicular regulatory (Tfr) cells. We compare the effects of Tfr cells in an in vitro model of bystander Tfh function in...
Main Authors: | Maria Lopez-Ocasio, Maja Buszko, Melissa Blain, Ke Wang, Ethan M. Shevach |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.00637/full |
Similar Items
-
CD4 T Follicular Helper and Regulatory Cell Dynamics and Function in HIV Infection
by: Miles, Brodie, et al.
Published: (2016) -
The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells
by: Elizabeth F. Wallin, et al.
Published: (2018-05-01) -
Unexpected Help: Follicular Regulatory T Cells in the Germinal Center
by: Markus M. Xie, et al.
Published: (2018-07-01) -
Are Follicular Regulatory T Cells Involved in Autoimmune Diseases?
by: Yonglu Gong, et al.
Published: (2017-12-01) -
Molecular cues govern follicular regulatory T cell differentiation
by: LIU Xindong, et al.
Published: (2020-12-01)