Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization.
Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectively. Alpha p...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1801076?pdf=render |