Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours

Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours

Circulating myeloid cells can leave the vasculature to infiltrate tumours and are thought to contribute to tumour angiogenesis. Here the authors live image monocytes that migrate to xenograft tumours and map an extravasation cascade of human proangiogenic monocytes into the tumour.

Bibliographic Details
Main Authors: Adama Sidibe, Patricia Ropraz, Stéphane Jemelin, Yalin Emre, Marine Poittevin, Marc Pocard, Paul F. Bradfield, Beat A. Imhof
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02610-0
Description
Summary:Circulating myeloid cells can leave the vasculature to infiltrate tumours and are thought to contribute to tumour angiogenesis. Here the authors live image monocytes that migrate to xenograft tumours and map an extravasation cascade of human proangiogenic monocytes into the tumour.
ISSN:2041-1723

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