Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience
<p>Abstract</p> <p>Background</p> <p>Adenocarcinoma of the small bowel is a relatively rare malignancy as compared to the other malignancies of the gastrointestinal tract. Nonspecific presentation and infrequent occurrence often leads to a delay in diagnosis and consequ...
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doaj-03297595a7fc474c837ab578b0f7cffe2020-11-24T22:38:21ZengBMCWorld Journal of Surgical Oncology1477-78192008-01-01611210.1186/1477-7819-6-12Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experienceJacobs Michael JCheung Laurence YJain Akhilesh KChaiyasate KongkritMittal Vijay K<p>Abstract</p> <p>Background</p> <p>Adenocarcinoma of the small bowel is a relatively rare malignancy as compared to the other malignancies of the gastrointestinal tract. Nonspecific presentation and infrequent occurrence often leads to a delay in diagnosis and consequent poor prognosis. Various other factors are of prognostic importance while managing these tumors.</p> <p>Methods</p> <p>The medical records of a total of 27 patients treated for adenocarcinoma of the small bowel at Providence Hospital and Medical Centers from year 1990 through 2003 were reviewed retrospectively. Data were analyzed using SPSS software (version 10.0; SPSS, Inc., Chicago, IL). Survival analyses were calculated using the Kaplan Meier method with the log rank test to assess the statistical significance. The socio-demographics (age, gender) were calculated using frequency analyses.</p> <p>Results</p> <p>The patients included nine males and eighteen females with a median age at diagnosis of 62 years. Only 48% of the patients had an accurate preoperative diagnosis while another 33% had a diagnosis suspicious of small bowel malignancy. None of the patients presented in stage 1. The cumulative five-year survival was 30% while the median survival was 3.3 years. There was no 30-day mortality in the postoperative period in our series.</p> <p>Conclusion</p> <p>The univariate analysis demonstrated that tumor grade, stage at presentation, lymph nodal metastasis and resection margins were significant predictors of survival.</p> http://www.wjso.com/content/6/1/12 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jacobs Michael J Cheung Laurence Y Jain Akhilesh K Chaiyasate Kongkrit Mittal Vijay K |
spellingShingle |
Jacobs Michael J Cheung Laurence Y Jain Akhilesh K Chaiyasate Kongkrit Mittal Vijay K Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience World Journal of Surgical Oncology |
author_facet |
Jacobs Michael J Cheung Laurence Y Jain Akhilesh K Chaiyasate Kongkrit Mittal Vijay K |
author_sort |
Jacobs Michael J |
title |
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
title_short |
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
title_full |
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
title_fullStr |
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
title_full_unstemmed |
Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
title_sort |
prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience |
publisher |
BMC |
series |
World Journal of Surgical Oncology |
issn |
1477-7819 |
publishDate |
2008-01-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Adenocarcinoma of the small bowel is a relatively rare malignancy as compared to the other malignancies of the gastrointestinal tract. Nonspecific presentation and infrequent occurrence often leads to a delay in diagnosis and consequent poor prognosis. Various other factors are of prognostic importance while managing these tumors.</p> <p>Methods</p> <p>The medical records of a total of 27 patients treated for adenocarcinoma of the small bowel at Providence Hospital and Medical Centers from year 1990 through 2003 were reviewed retrospectively. Data were analyzed using SPSS software (version 10.0; SPSS, Inc., Chicago, IL). Survival analyses were calculated using the Kaplan Meier method with the log rank test to assess the statistical significance. The socio-demographics (age, gender) were calculated using frequency analyses.</p> <p>Results</p> <p>The patients included nine males and eighteen females with a median age at diagnosis of 62 years. Only 48% of the patients had an accurate preoperative diagnosis while another 33% had a diagnosis suspicious of small bowel malignancy. None of the patients presented in stage 1. The cumulative five-year survival was 30% while the median survival was 3.3 years. There was no 30-day mortality in the postoperative period in our series.</p> <p>Conclusion</p> <p>The univariate analysis demonstrated that tumor grade, stage at presentation, lymph nodal metastasis and resection margins were significant predictors of survival.</p> |
url |
http://www.wjso.com/content/6/1/12 |
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