Cardiac manifestations of COVID-19
COVID-19 is a novel viral infection caused by severe acute respiratory syndrome (SARS) beta-coronavirus. Epidemiological status changes dynamically as the pandemy is far from ending. Several complications of presented virus may be similar to those observed in other viral infections. Despite lacki...
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doaj-032fd1e6f7e24ab9a9beac4ebc3a18182021-07-14T08:59:38ZengIMR (Innovative Medical Research) Press LimitedReviews in Cardiovascular Medicine2153-81742021-06-0122236537110.31083/j.rcm22020431625013557398-1366351761Cardiac manifestations of COVID-19Agata Bielecka-Dabrowa0Anna Cichocka-Radwan1Joanna Lewek2Filip Pawliczak3Marek Maciejewski4Maciej Banach5Department of Preventive Cardiology and Lipidology, Chair of Nephrology and Hypertension, Medical University of Lodz, Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Cardiology and Congenital Diseases of Adults, Heart Failure Unit, Polish Mother’s Memorial Hospital Research Institute (PMMHRI), Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Preventive Cardiology and Lipidology, Chair of Nephrology and Hypertension, Medical University of Lodz, Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Preventive Cardiology and Lipidology, Chair of Nephrology and Hypertension, Medical University of Lodz, Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Cardiology and Congenital Diseases of Adults, Heart Failure Unit, Polish Mother’s Memorial Hospital Research Institute (PMMHRI), Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Preventive Cardiology and Lipidology, Chair of Nephrology and Hypertension, Medical University of Lodz, Rzgowska 281/289, 93-338 Lodz, PolandCOVID-19 is a novel viral infection caused by severe acute respiratory syndrome (SARS) beta-coronavirus. Epidemiological status changes dynamically as the pandemy is far from ending. Several complications of presented virus may be similar to those observed in other viral infections. Despite lacking data, the heart involvement may be comparable to cardiac complications observed previously in those with SARS as well as Middle East Respiratory Syndrome (MERS). In COVID-19 we observe elevated levels of cardiac biomarkers, such as natriuretic peptides, troponins, myoglobin, C-reactive protein (CRP), interleukin-2 (IL-2), interleukin-6 (IL-6) and ferritin, which is likely the result of myocardial injury. The possible mechanisms of cardiovascular injury include direct toxicity through the viral invasion of cardiac myocytes, ACE-2 receptor-mediated CV (cardiac and endothelial) injury, microvascular dysfunction and thrombosis and cytokine release syndrome (mainly IL-6 mediated). Cardiac manifestations of COVID-19 are focal or global myocardial inflammation, necrosis, ventricular dysfunction, heart failure and arrhythmia.https://rcm.imrpress.com/fileup/2153-8174/PDF/1625013557398-1366351761.pdfcovid-19coronavirussars-cov-2heart failurecardiac manifestations |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Agata Bielecka-Dabrowa Anna Cichocka-Radwan Joanna Lewek Filip Pawliczak Marek Maciejewski Maciej Banach |
spellingShingle |
Agata Bielecka-Dabrowa Anna Cichocka-Radwan Joanna Lewek Filip Pawliczak Marek Maciejewski Maciej Banach Cardiac manifestations of COVID-19 Reviews in Cardiovascular Medicine covid-19 coronavirus sars-cov-2 heart failure cardiac manifestations |
author_facet |
Agata Bielecka-Dabrowa Anna Cichocka-Radwan Joanna Lewek Filip Pawliczak Marek Maciejewski Maciej Banach |
author_sort |
Agata Bielecka-Dabrowa |
title |
Cardiac manifestations of COVID-19 |
title_short |
Cardiac manifestations of COVID-19 |
title_full |
Cardiac manifestations of COVID-19 |
title_fullStr |
Cardiac manifestations of COVID-19 |
title_full_unstemmed |
Cardiac manifestations of COVID-19 |
title_sort |
cardiac manifestations of covid-19 |
publisher |
IMR (Innovative Medical Research) Press Limited |
series |
Reviews in Cardiovascular Medicine |
issn |
2153-8174 |
publishDate |
2021-06-01 |
description |
COVID-19 is a novel viral infection caused by severe acute respiratory syndrome
(SARS) beta-coronavirus. Epidemiological status changes dynamically as the
pandemy is far from ending. Several complications of presented virus may be
similar to those observed in other viral infections. Despite lacking data, the
heart involvement may be comparable to cardiac complications observed previously
in those with SARS as well as Middle East Respiratory Syndrome (MERS). In
COVID-19 we observe elevated levels of cardiac biomarkers, such as natriuretic
peptides, troponins, myoglobin, C-reactive protein (CRP), interleukin-2 (IL-2),
interleukin-6 (IL-6) and ferritin, which is likely the result of myocardial
injury. The possible mechanisms of cardiovascular injury include direct toxicity
through the viral invasion of cardiac myocytes, ACE-2 receptor-mediated CV
(cardiac and endothelial) injury, microvascular dysfunction and thrombosis and
cytokine release syndrome (mainly IL-6 mediated). Cardiac manifestations of
COVID-19 are focal or global myocardial inflammation, necrosis, ventricular
dysfunction, heart failure and arrhythmia. |
topic |
covid-19 coronavirus sars-cov-2 heart failure cardiac manifestations |
url |
https://rcm.imrpress.com/fileup/2153-8174/PDF/1625013557398-1366351761.pdf |
work_keys_str_mv |
AT agatabieleckadabrowa cardiacmanifestationsofcovid19 AT annacichockaradwan cardiacmanifestationsofcovid19 AT joannalewek cardiacmanifestationsofcovid19 AT filippawliczak cardiacmanifestationsofcovid19 AT marekmaciejewski cardiacmanifestationsofcovid19 AT maciejbanach cardiacmanifestationsofcovid19 |
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