Safety and Efficacy of Reduced Prolonged-release Tacrolimus Exposure in De Novo Kidney Transplantation: A Randomized, Open-label, Pilot Study in Asia—OPTIMIZE Study

Safety and Efficacy of Reduced Prolonged-release Tacrolimus Exposure in De Novo Kidney Transplantation: A Randomized, Open-label, Pilot Study in Asia—OPTIMIZE Study

Background. A multicenter, randomized, open-label, parallel group, pilot, 52-week study in Asian countries that assessed the renal function, efficacy, and safety of reduced-exposure versus standard-exposure prolonged-release tacrolimus (PR-T) in adult kidney transplant recipients (KTRs). Methods. Po...

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Bibliographic Details
Main Authors: Young Hoon Kim, MD, Yang-Jen Chiang, MD, Sung-Joo Kim, MD, PhD, Myoung Soo Kim, MD, PhD, Sung Bae Park, MD, PhD, Sheng-Tang Wu, MD, Kazuhiro Horita, Yoshihiro Nakashima, Hongsi Jiang, MD, PhD, Duck-Jong Han, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2019-04-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000877

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