Composite Lymphoma in a Patient with Ulcerative Colitis: A Case Report

• Main Authors: Farzaneh Ashrafi, Farid Kowsari, Ali Darakhshandeh, Peyman Adibi
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2014-12-01
• Series: International Journal of Hematology-Oncology and Stem Cell Research
• Subjects: Composite lymphoma; Diffuse large B-Cell lymphoma; Inflammatory bowel disease; Nodular sclerosing Hodgkin lymphoma; Ulcerative colitis
• Online Access: https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/404

A 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. Only mesalamine kept ulcerative colitis under control. In physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. Computed tomography scan revealed para-aortic mediastinal lymphadenopathy with splenomegaly. Splenectomy and excisional biopsy of abdominal lymph node were performed and disease was diagnosed as composite lymphoma, consisting of diffuse large B-cell lymphoma and nodular sclerosing Hodgkin lymphoma.