Polyethylene-Based Knee Spacer for Infection Control: Design Concept and Pre-Clinical In Vitro Validations

Polyethylene-Based Knee Spacer for Infection Control: Design Concept and Pre-Clinical In Vitro Validations

Antibiotic-loaded polymethyl methacrylate (PMMA) has been widely applied in the treatment of knee periprosthetic joint infections. However, problems with antibiotic-loaded PMMA-based spacers, such as structural fracture and implant dislocation, remain unresolved. A novel polyethylene-based spacer, d...

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Bibliographic Details
Main Authors: Yuhan Chang, Mel S. Lee, Jiann-Jong Liau, Yu-Liang Liu, Wen-Chuan Chen, Steve W. N. Ueng
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Polymers
Subjects:
periprosthetic joint infection
two-stage exchange arthroplasty
knee spacer
polyethylene
cement
fatigue
Online Access:https://www.mdpi.com/2073-4360/12/10/2334

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