Current understanding of the glial response to disorders of the aging CNS

In this special issue of Frontiers in Neuropharmacology, we have asked leading experts to comment and review the evidence that inflammatory cells play a leading role in the pathological processes underlying neurodegenerative disorders. We now seek to draw these various observations together into a c...

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Main Authors: Francesca eCicchetti, Roger A Barker
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00095/full
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spelling doaj-036b7f9cf16b4573846d0a51e70aad2f2020-11-24T21:17:14ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122012-05-01310.3389/fphar.2012.0009526955Current understanding of the glial response to disorders of the aging CNSFrancesca eCicchetti0Roger A Barker1Centre de recherche du CHUL (CHUQ)/Université LavalCambridge Centre for Brain Repair, University of CambridgeIn this special issue of Frontiers in Neuropharmacology, we have asked leading experts to comment and review the evidence that inflammatory cells play a leading role in the pathological processes underlying neurodegenerative disorders. We now seek to draw these various observations together into a conclusion, with the hope that this will inform further work in this area and lead to the identification of new therapeutic targets that will have a disease modifying effect.http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00095/fullInflammationMicrogliaAlzheimer's diseaseParkinson's diseaseHuntington's diseaseMotorneuron disease
collection DOAJ
language English
format Article
sources DOAJ
author Francesca eCicchetti
Roger A Barker
spellingShingle Francesca eCicchetti
Roger A Barker
Current understanding of the glial response to disorders of the aging CNS
Frontiers in Pharmacology
Inflammation
Microglia
Alzheimer's disease
Parkinson's disease
Huntington's disease
Motorneuron disease
author_facet Francesca eCicchetti
Roger A Barker
author_sort Francesca eCicchetti
title Current understanding of the glial response to disorders of the aging CNS
title_short Current understanding of the glial response to disorders of the aging CNS
title_full Current understanding of the glial response to disorders of the aging CNS
title_fullStr Current understanding of the glial response to disorders of the aging CNS
title_full_unstemmed Current understanding of the glial response to disorders of the aging CNS
title_sort current understanding of the glial response to disorders of the aging cns
publisher Frontiers Media S.A.
series Frontiers in Pharmacology
issn 1663-9812
publishDate 2012-05-01
description In this special issue of Frontiers in Neuropharmacology, we have asked leading experts to comment and review the evidence that inflammatory cells play a leading role in the pathological processes underlying neurodegenerative disorders. We now seek to draw these various observations together into a conclusion, with the hope that this will inform further work in this area and lead to the identification of new therapeutic targets that will have a disease modifying effect.
topic Inflammation
Microglia
Alzheimer's disease
Parkinson's disease
Huntington's disease
Motorneuron disease
url http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00095/full
work_keys_str_mv AT francescaecicchetti currentunderstandingoftheglialresponsetodisordersoftheagingcns
AT rogerabarker currentunderstandingoftheglialresponsetodisordersoftheagingcns
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