Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital
Tuberculosis appears to be a disease as old as human history. Tuberculosis is of great public health importance in the developing countries. Its clinical profile is different in developing countries in comparison to countries of Europe and North America. The recent epidemic of HIV has slowed down th...
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Tehran University of Medical Sciences
1999-07-01
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doaj-036d911d271b4321b8f00c8275fd85b12020-11-24T23:10:01ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73221999-07-015724952Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini HospitalDaneshjoo KhTuberculosis appears to be a disease as old as human history. Tuberculosis is of great public health importance in the developing countries. Its clinical profile is different in developing countries in comparison to countries of Europe and North America. The recent epidemic of HIV has slowed down the declining trend in the incidence of tuberculosis. Bacilli are transmitted from one infected person to the others as an aerosol. In some cases contaminated milk may also be responsible. However despite effective regimens and addition of new drugs and improved pharmacokinetic knowledge the chemotherapy of tuberculosis still remains a challenge. Poor drug-compliance by patients being one of the foremost reason for frequent relapses and bacterial resistance. Some important and concrete steps to meet these challenges have been judicious use of two or more bactericidal drugs and introduction of short courses regiment. Multiple drugs therapy may shorten the duration of treatment and prevent emergence of drug resistance. http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5679.pdf&manuscript_id=5679Short course therapy |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
Daneshjoo Kh |
spellingShingle |
Daneshjoo Kh Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital Tehran University Medical Journal Short course therapy |
author_facet |
Daneshjoo Kh |
author_sort |
Daneshjoo Kh |
title |
Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital |
title_short |
Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital |
title_full |
Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital |
title_fullStr |
Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital |
title_full_unstemmed |
Evaluation of short course drug therapy for tuberculosis in pediatric ward of Imam Khomeini Hospital |
title_sort |
evaluation of short course drug therapy for tuberculosis in pediatric ward of imam khomeini hospital |
publisher |
Tehran University of Medical Sciences |
series |
Tehran University Medical Journal |
issn |
1683-1764 1735-7322 |
publishDate |
1999-07-01 |
description |
Tuberculosis appears to be a disease as old as human history. Tuberculosis is of great public health importance in the developing countries. Its clinical profile is different in developing countries in comparison to countries of Europe and North America. The recent epidemic of HIV has slowed down the declining trend in the incidence of tuberculosis. Bacilli are transmitted from one infected person to the others as an aerosol. In some cases contaminated milk may also be responsible. However despite effective regimens and addition of new drugs and improved pharmacokinetic knowledge the chemotherapy of tuberculosis still remains a challenge. Poor drug-compliance by patients being one of the foremost reason for frequent relapses and bacterial resistance. Some important and concrete steps to meet these challenges have been judicious use of two or more bactericidal drugs and introduction of short courses regiment. Multiple drugs therapy may shorten the duration of treatment and prevent emergence of drug resistance. |
topic |
Short course therapy |
url |
http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5679.pdf&manuscript_id=5679 |
work_keys_str_mv |
AT daneshjookh evaluationofshortcoursedrugtherapyfortuberculosisinpediatricwardofimamkhomeinihospital |
_version_ |
1725608585728098304 |