Short-Term and Long-Term Outcomes of Kidney Transplantation in Diabetic and Nondiabetic Patients

• Main Authors: Hajieh Shahbazian, Heshmatollah Shahbazian
• Format: Article
• Language: English
• Published: Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences 2005-04-01
• Series: Urology Journal
• Online Access: http://www.urologyjournal.org/index.php/uj/article/view/224/221

<p class="MsoNormal" style="margin: 14pt 0cm;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong><span style="mso-bidi-language: FA;">Introduction:</span></strong><span style="mso-bidi-language: FA;"> The purpose of this study was to compare the short-term and long-term kidney transplant outcomes in diabetic and nondiabetic patients.</span></span></span></p><p class="MsoNormal" style="margin: 14pt 0cm;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong><span style="mso-bidi-language: FA;">Materials and Methods: </span></strong><span style="mso-bidi-language: FA;">We studied all kidney recipients in Golestan hospital, Ahwaz, from 1995 to 2003. The patients were divided into two groups of diabetic and nondiabetic, and 1-year, 2-year, and 5-year survival rates of the patient and the kidney were evaluated. We also evaluated and compared the causes of death between these two groups.</span></span></span></p><p class="MsoNormal" style="margin: 14pt 0cm;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong><span style="mso-bidi-language: FA;">Results: </span></strong><span style="mso-bidi-language: FA;">There were 50 diabetic patients with a mean age of 51 years, and 350 nondiabetic patients with the mean age of 29 years old (<em>P</em> = .03). One-year, 2-year, and 5-year graft survival rates were 90% versus 91.5%, 86% versus 89%, and 76% versus 83% in diabetic and nondiabetic patients, respectively (<em>P</em> = .19). The patient survival rates were 92% versus 93%, 88% versus 91%, and 76% versus 84% in diabetic and nondiabetic patients, respectively. The most common cause of death was myocardial infarction in diabetic patients (50%), and septicemia among the nondiabetic ones (50%). The most common cause of kidney allograft loss was patient's death (75%) in diabetic patients and kidney rejection (40%) in nondiabetics.</span></span></span></p><p class="MsoNormal" style="margin: 14pt 0cm;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong><span style="mso-bidi-language: FA;">Conclusion: </span></strong><span style="mso-bidi-language: FA;">Long-term kidney transplantation results have been significantly improved comparing with other studies. Thus, kidney transplantation is recommended as the<span style="mso-spacerun: yes;"> </span>treatment of choice in diabetic patients with end-stage renal disease. However, a complete evaluation of cardiac problems for these patients is recommended before the surgery.</span></span></span></p>