Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling

Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling

<i>Background:</i> The endothelial epsin 1 and 2 endocytic adaptor proteins play an important role in atherosclerosis by regulating the degradation of the calcium release channel inositol 1,4,5-trisphosphate receptor type 1 (IP3R1). In this study, we sought to identify additional targets...

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Bibliographic Details
Main Authors: Yunzhou Dong, Beibei Wang, Kui Cui, Xiaofeng Cai, Sudarshan Bhattacharjee, Scott Wong, Douglas B. Cowan, Hong Chen
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
epsin
adaptor protein
endocytosis
adhesion molecule
selectin
MCP-1
Online Access:https://www.mdpi.com/2073-4409/10/8/1918

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