Optical Characterization of Oligonucleotide DNA Influenced by Magnetic Fields

• Main Authors: Seyedeh Maryam Banihashemian, Vengadesh Periasamy, Seyed Mohammad Hossein Mousa Kazemi Mohammadi, Richard Ritikos, Saadah Abdul Rahman
• Format: Article
• Language: English
• Published: MDPI AG 2013-09-01
• Series: Molecules
• Subjects: oligonucleotide DNA; magnetic field; refractive index; extinction coefficient
• Online Access: http://www.mdpi.com/1420-3049/18/10/11797

UV-VIS spectroscopic analysis of oligonucleotide DNA exposed to different magnetic fields was performed in order to investigate the relationship between DNA extinction coefficients and optical parameters according to magnetic-field strength. The results with the oligonucleotides adenine-thymine 100 mer (AT-100 DNA) and cytosine-guanine 100 mer (CG-100 DNA) indicate that the magnetic field influences DNA molar extinction coefficients and refractive indexes. The imaginary parts of the refractive index and molar extinction coefficients of the AT-100 and CG-100 DNA decreased after exposure to a magnetic field of 750 mT due to cleavage of the DNA oligonucleotides into smaller segments.