Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration

Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration

Pulmonary arterial hypertension (PAH) is a complex degenerative disorder marked by aberrant vascular remodeling associated with hyperproliferation and migration of endothelial cells (ECs). Previous reports implicated bone morphogenetic protein antagonist Gremlin 1 in this process; however, little is...

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Bibliographic Details
Main Authors:	Daniel S. de Jesus, Evan DeVallance, Yao Li, Micol Falabella, Danielle Guimaraes, Sruti Shiva, Brett A. Kaufman, Mark T. Gladwin, Patrick J. Pagano
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Series:	Redox Biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231718308929

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