Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

<h4>Background</h4>We have previously shown that multiple genetic loci identified by genome-wide association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It is, however, not known whether and to what extent this genetic susceptibility may be attenuated by...

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Bibliographic Details
Main Authors: Shengxu Li, Jing Hua Zhao, Jian'an Luan, Ulf Ekelund, Robert N Luben, Kay-Tee Khaw, Nicholas J Wareham, Ruth J F Loos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20824172/pdf/?tool=EBI