Impact of arrhythmogenic calmodulin variants on small conductance Ca2+‐activated K+ (SK3) channels

Impact of arrhythmogenic calmodulin variants on small conductance Ca2+‐activated K+ (SK3) channels

Abstract Calmodulin (CaM) is a ubiquitous Ca2+‐sensing protein regulating many important cellular processes. Several CaM‐associated variants have been identified in a small group of patients with cardiac arrhythmias. The mechanism remains largely unknown, even though a number of ion channels, includ...

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Bibliographic Details
Main Authors: Arnela Saljic, Kalai Mangai Muthukumarasamy, Jonas Marstrand laCour, Kim Boddum, Morten Grunnet, Martin Werner Berchtold, Thomas Jespersen
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Physiological Reports
Subjects:
Calmodulin
cardiac arrhythmias
channelopathies
CPVT
LQTS
small conductance Ca+‐activated K+ channels
Online Access:https://doi.org/10.14814/phy2.14210

Internet

https://doi.org/10.14814/phy2.14210

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