Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells
1,2-unsaturated pyrrolizidine alkaloids (PAs) are secondary plant metabolites occurring as food contaminants that can cause severe liver damage upon metabolic activation in hepatocytes. However, it is yet unknown how these contaminants enter the cells. The role of hepatic transporters is only at the...
Main Authors: | Anne-Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Albert Braeuning, Stefanie Hessel-Pras |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/8/3821 |
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