Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration[S]
Retinal degeneration (RD) affects millions of people and is a major cause of ocular impairment and blindness. With a wide range of mutations and conditions leading to degeneration, targeting downstream processes is necessary for developing effective treatments. Ceramide and sphingosine-1-phosphate,...
Main Authors: | Megan Stiles, Hui Qi, Eleanor Sun, Jeremy Tan, Hunter Porter, Jeremy Allegood, Charles E. Chalfant, Douglas Yasumura, Michael T. Matthes, Matthew M. LaVail, Nawajes A. Mandal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520309858 |
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