Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
Epigenetic perturbations may be an important factor in diseases where both genes and environment play a role. Here, Ventham and colleagues show that DNA methylation changes in inflammatory bowel disease are related to the underlying genotype, and are associated with cell-specific changes to gene exp...
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Bibliographic Details
| Main Authors: |
N. T. Ventham,
N. A. Kennedy,
A. T. Adams,
R. Kalla,
S. Heath,
K. R. O'Leary,
H. Drummond,
IBD BIOM consortium,
IBD CHARACTER consortium,
D. C. Wilson,
I. G. Gut,
E. R. Nimmo,
J. Satsangi |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2016-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms13507
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