Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions.

Langerhans cell histiocytosis (LCH) is a complex and poorly understood disorder that has characteristics of both inflammatory and neoplastic disease. By using eight-colour flow cytometry, we have identified a previously unreported population of CD1a(+)/CD3(+) T-cells in LCH lesions. The expression o...

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Bibliographic Details
Main Authors: Jennifer A West, Sharon L Olsen, Jenée M Mitchell, Ross E Priddle, Jennifer M Luke, Selma Olsson Akefeldt, Jan-Inge Henter, Christopher Turville, George Kannourakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4208746?pdf=render