Cobalamin Deficiency in Elderly Patients: A Personal View
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age) but is often unrecognized because its clinical manifestations are subtle; however, they are also potentially serious, particularly from a neuropsychiatric and hematological perspective. In the elderly, the...
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doaj-03fc35c4865046da81622cfddd21c2c02020-11-24T23:44:22ZengHindawi LimitedCurrent Gerontology and Geriatrics Research1687-70631687-70712008-01-01200810.1155/2008/848267848267Cobalamin Deficiency in Elderly Patients: A Personal ViewEmmanuel Andrès0Thomas Vogel1Laure Federici2Jacques Zimmer3Ecaterina Ciobanu4Georges Kaltenbach5Department of Internal Medicine, Diabetes, and Metabolic Diseases, University Hospital of Strasbourg, 67091 Strasbourg, FranceDepartment of Internal Medicine and Geriatrics, University Hospital of Strasbourg, 67091 Strasbourg, FranceDepartment of Internal Medicine, Diabetes, and Metabolic Diseases, University Hospital of Strasbourg, 67091 Strasbourg, FranceLaboratoire d'Immunogénétique-Allergologie, Centre de Recherche Public de la Santé (CRP-Santé) de Luxembourg, 1526 Luxembourg, LuxembourgDepartment of Internal Medicine, Diabetes, and Metabolic Diseases, University Hospital of Strasbourg, 67091 Strasbourg, FranceDepartment of Internal Medicine and Geriatrics, University Hospital of Strasbourg, 67091 Strasbourg, FranceCobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age) but is often unrecognized because its clinical manifestations are subtle; however, they are also potentially serious, particularly from a neuropsychiatric and hematological perspective. In the elderly, the main causes of cobalamin deficiency are pernicious anemia and food-cobalamin malabsorption. Food-cobalamin malabsorption syndrome is a disorder characterized by the inability to release cobalamin from food or its binding proteins. This syndrome is usually caused by atrophic gastritis, related or unrelated to Helicobacter pylori infection, and long-term ingestion of antacids and biguanides. Management of cobalamin deficiency with cobalamin injections is currently well documented but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption.http://dx.doi.org/10.1155/2008/848267 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Emmanuel Andrès Thomas Vogel Laure Federici Jacques Zimmer Ecaterina Ciobanu Georges Kaltenbach |
spellingShingle |
Emmanuel Andrès Thomas Vogel Laure Federici Jacques Zimmer Ecaterina Ciobanu Georges Kaltenbach Cobalamin Deficiency in Elderly Patients: A Personal View Current Gerontology and Geriatrics Research |
author_facet |
Emmanuel Andrès Thomas Vogel Laure Federici Jacques Zimmer Ecaterina Ciobanu Georges Kaltenbach |
author_sort |
Emmanuel Andrès |
title |
Cobalamin Deficiency in Elderly Patients: A Personal View |
title_short |
Cobalamin Deficiency in Elderly Patients: A Personal View |
title_full |
Cobalamin Deficiency in Elderly Patients: A Personal View |
title_fullStr |
Cobalamin Deficiency in Elderly Patients: A Personal View |
title_full_unstemmed |
Cobalamin Deficiency in Elderly Patients: A Personal View |
title_sort |
cobalamin deficiency in elderly patients: a personal view |
publisher |
Hindawi Limited |
series |
Current Gerontology and Geriatrics Research |
issn |
1687-7063 1687-7071 |
publishDate |
2008-01-01 |
description |
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age) but is often unrecognized because its clinical manifestations are subtle; however, they are also potentially serious, particularly from a neuropsychiatric and hematological perspective. In the elderly, the main causes of cobalamin deficiency are pernicious anemia and food-cobalamin malabsorption. Food-cobalamin malabsorption syndrome is a disorder characterized by the inability to release cobalamin from food or its binding proteins. This syndrome is usually caused by atrophic gastritis, related or unrelated to Helicobacter pylori infection, and long-term ingestion of antacids and biguanides. Management of cobalamin deficiency with cobalamin injections is currently well documented but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption. |
url |
http://dx.doi.org/10.1155/2008/848267 |
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