The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses
The envelope glycoprotein M (gM), a surface virion component conserved among alphaherpesviruses, is a multiple-transmembrane domain-containing glycoprotein with a complex N-linked oligosaccharide. The gM mediates a diverse range of functions during the viral life cycle. In this review, we summarize...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2021.631523/full |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Chunmei Li Chunmei Li Chunmei Li Mingshu Wang Mingshu Wang Mingshu Wang Anchun Cheng Anchun Cheng Anchun Cheng Renyong Jia Renyong Jia Renyong Jia Qiao Yang Qiao Yang Qiao Yang Ying Wu Ying Wu Ying Wu Dekang Zhu Dekang Zhu Xinxin Zhao Xinxin Zhao Xinxin Zhao Shun Chen Shun Chen Shun Chen Mafeng Liu Mafeng Liu Mafeng Liu Shaqiu Zhang Shaqiu Zhang Shaqiu Zhang Xumin Ou Xumin Ou Xumin Ou Sai Mao Sai Mao Sai Mao Qun Gao Qun Gao Qun Gao Di Sun Di Sun Di Sun Xingjian Wen Xingjian Wen Xingjian Wen Bin Tian Bin Tian |
| spellingShingle |
Chunmei Li Chunmei Li Chunmei Li Mingshu Wang Mingshu Wang Mingshu Wang Anchun Cheng Anchun Cheng Anchun Cheng Renyong Jia Renyong Jia Renyong Jia Qiao Yang Qiao Yang Qiao Yang Ying Wu Ying Wu Ying Wu Dekang Zhu Dekang Zhu Xinxin Zhao Xinxin Zhao Xinxin Zhao Shun Chen Shun Chen Shun Chen Mafeng Liu Mafeng Liu Mafeng Liu Shaqiu Zhang Shaqiu Zhang Shaqiu Zhang Xumin Ou Xumin Ou Xumin Ou Sai Mao Sai Mao Sai Mao Qun Gao Qun Gao Qun Gao Di Sun Di Sun Di Sun Xingjian Wen Xingjian Wen Xingjian Wen Bin Tian Bin Tian The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses Frontiers in Microbiology alphaherpesviruses glycoprotein M entry fusion the viral life cycles |
| author_facet |
Chunmei Li Chunmei Li Chunmei Li Mingshu Wang Mingshu Wang Mingshu Wang Anchun Cheng Anchun Cheng Anchun Cheng Renyong Jia Renyong Jia Renyong Jia Qiao Yang Qiao Yang Qiao Yang Ying Wu Ying Wu Ying Wu Dekang Zhu Dekang Zhu Xinxin Zhao Xinxin Zhao Xinxin Zhao Shun Chen Shun Chen Shun Chen Mafeng Liu Mafeng Liu Mafeng Liu Shaqiu Zhang Shaqiu Zhang Shaqiu Zhang Xumin Ou Xumin Ou Xumin Ou Sai Mao Sai Mao Sai Mao Qun Gao Qun Gao Qun Gao Di Sun Di Sun Di Sun Xingjian Wen Xingjian Wen Xingjian Wen Bin Tian Bin Tian |
| author_sort |
Chunmei Li |
| title |
The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses |
| title_short |
The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses |
| title_full |
The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses |
| title_fullStr |
The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses |
| title_full_unstemmed |
The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses |
| title_sort |
roles of envelope glycoprotein m in the life cycle of some alphaherpesviruses |
| publisher |
Frontiers Media S.A. |
| series |
Frontiers in Microbiology |
| issn |
1664-302X |
| publishDate |
2021-02-01 |
| description |
The envelope glycoprotein M (gM), a surface virion component conserved among alphaherpesviruses, is a multiple-transmembrane domain-containing glycoprotein with a complex N-linked oligosaccharide. The gM mediates a diverse range of functions during the viral life cycle. In this review, we summarize the biological features of gM, including its characterization and function in some specicial alphaherpesviruses. gM modulates the virus-induced membrane fusion during virus invasion, transports other proteins to the appropriate intracellular membranes for primary and secondary envelopment during virion assembly, and promotes egress of the virus. The gM can interact with various viral and cellular components, and the focus of recent research has also been on interactions related to gM. And we will discuss how gM participates in the life cycle of alphaherpesviruses. |
| topic |
alphaherpesviruses glycoprotein M entry fusion the viral life cycles |
| url |
https://www.frontiersin.org/articles/10.3389/fmicb.2021.631523/full |
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doaj-0411b680a5e5476e8f25280d5d9ff9502021-02-19T06:28:39ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2021-02-011210.3389/fmicb.2021.631523631523The Roles of Envelope Glycoprotein M in the Life Cycle of Some AlphaherpesvirusesChunmei Li0Chunmei Li1Chunmei Li2Mingshu Wang3Mingshu Wang4Mingshu Wang5Anchun Cheng6Anchun Cheng7Anchun Cheng8Renyong Jia9Renyong Jia10Renyong Jia11Qiao Yang12Qiao Yang13Qiao Yang14Ying Wu15Ying Wu16Ying Wu17Dekang Zhu18Dekang Zhu19Xinxin Zhao20Xinxin Zhao21Xinxin Zhao22Shun Chen23Shun Chen24Shun Chen25Mafeng Liu26Mafeng Liu27Mafeng Liu28Shaqiu Zhang29Shaqiu Zhang30Shaqiu Zhang31Xumin Ou32Xumin Ou33Xumin Ou34Sai Mao35Sai Mao36Sai Mao37Qun Gao38Qun Gao39Qun Gao40Di Sun41Di Sun42Di Sun43Xingjian Wen44Xingjian Wen45Xingjian Wen46Bin Tian47Bin Tian48Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, ChinaThe envelope glycoprotein M (gM), a surface virion component conserved among alphaherpesviruses, is a multiple-transmembrane domain-containing glycoprotein with a complex N-linked oligosaccharide. The gM mediates a diverse range of functions during the viral life cycle. In this review, we summarize the biological features of gM, including its characterization and function in some specicial alphaherpesviruses. gM modulates the virus-induced membrane fusion during virus invasion, transports other proteins to the appropriate intracellular membranes for primary and secondary envelopment during virion assembly, and promotes egress of the virus. The gM can interact with various viral and cellular components, and the focus of recent research has also been on interactions related to gM. And we will discuss how gM participates in the life cycle of alphaherpesviruses.https://www.frontiersin.org/articles/10.3389/fmicb.2021.631523/fullalphaherpesvirusesglycoprotein Mentryfusionthe viral life cycles |