Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma

Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma

Abstract Background Herein, we investigate the relationship between pancreatic stem cell markers (PCSC markers), CD44, and epithelial-specific antigen (ESA), tumor stroma, and the impact on recurrence outcomes in pancreatic ductal adenocarcinoma (PDAC) patients. Methods PDAC patients who underwent s...

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Bibliographic Details
Main Authors: Gokce Askan, Ibrahim Halil. Sahin, Joanne F. Chou, Aslihan Yavas, Marinela Capanu, Christine A. Iacobuzio-Donahue, Olca Basturk, Eileen M. O’Reilly
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Pancreatic ductal adenocarcinoma
Pancreatic cancer
Cancer stem cells
Tumor stroma
Sonic hedgehog
Desmoplasia
Online Access:https://doi.org/10.1186/s12885-021-08123-w

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