Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis.
<h4>Background</h4>Extremely low frequency magnetic fields (ELF-MFs) are classified as a possible carcinogenic factor (Group 2B). This study assessed the association between ELF-MFs and childhood cancer through a systematic review and meta-analysis.<h4>Methods</h4>Three datab...
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doaj-042cf669c92e414a9e428f11885512322021-05-29T04:31:24ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01165e025162810.1371/journal.pone.0251628Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis.GyeongAe SeomunJuneyoung LeeJinkyung Park<h4>Background</h4>Extremely low frequency magnetic fields (ELF-MFs) are classified as a possible carcinogenic factor (Group 2B). This study assessed the association between ELF-MFs and childhood cancer through a systematic review and meta-analysis.<h4>Methods</h4>Three databases were searched in January 2020. We conducted a meta-analysis for the association between the ELF-MFs exposure level and childhood cancer.<h4>Results</h4>A total of 33 studies were identified. Thirty studies with 186,223 participants were included in the meta-analysis. Children exposed to 0.2-, 0.3-, and 0.4-μT ELF-MFs had a 1.26 (95% confidence interval [CI] 1.06-1.49), 1.22 (95% CI 0.93-1.61), and 1.72 (95% CI 1.25-2.35) times higher odds of childhood leukemia. In childhood brain tumors, children exposed to 0.2-μT had a 0.95 (95% CI 0.59-1.56) times higher odds, and those exposed to 0.4-μT ELF-MFs had a 1.25 (95% CI 0.93-1.61). Children exposed to 0.2- and 0.4-μT ELF-MFs had a 1.10 (95% CI 0.70-1.75) and 2.01 (95% CI 0.89-4.52) times higher odds of any childhood cancers.<h4>Conclusions</h4>Significant associations were observed between exposure to ELF-MFs and childhood leukemia. Furthermore, a possible dose-response effect was also observed.https://doi.org/10.1371/journal.pone.0251628 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
GyeongAe Seomun Juneyoung Lee Jinkyung Park |
spellingShingle |
GyeongAe Seomun Juneyoung Lee Jinkyung Park Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. PLoS ONE |
author_facet |
GyeongAe Seomun Juneyoung Lee Jinkyung Park |
author_sort |
GyeongAe Seomun |
title |
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. |
title_short |
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. |
title_full |
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. |
title_fullStr |
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. |
title_full_unstemmed |
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis. |
title_sort |
exposure to extremely low-frequency magnetic fields and childhood cancer: a systematic review and meta-analysis. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2021-01-01 |
description |
<h4>Background</h4>Extremely low frequency magnetic fields (ELF-MFs) are classified as a possible carcinogenic factor (Group 2B). This study assessed the association between ELF-MFs and childhood cancer through a systematic review and meta-analysis.<h4>Methods</h4>Three databases were searched in January 2020. We conducted a meta-analysis for the association between the ELF-MFs exposure level and childhood cancer.<h4>Results</h4>A total of 33 studies were identified. Thirty studies with 186,223 participants were included in the meta-analysis. Children exposed to 0.2-, 0.3-, and 0.4-μT ELF-MFs had a 1.26 (95% confidence interval [CI] 1.06-1.49), 1.22 (95% CI 0.93-1.61), and 1.72 (95% CI 1.25-2.35) times higher odds of childhood leukemia. In childhood brain tumors, children exposed to 0.2-μT had a 0.95 (95% CI 0.59-1.56) times higher odds, and those exposed to 0.4-μT ELF-MFs had a 1.25 (95% CI 0.93-1.61). Children exposed to 0.2- and 0.4-μT ELF-MFs had a 1.10 (95% CI 0.70-1.75) and 2.01 (95% CI 0.89-4.52) times higher odds of any childhood cancers.<h4>Conclusions</h4>Significant associations were observed between exposure to ELF-MFs and childhood leukemia. Furthermore, a possible dose-response effect was also observed. |
url |
https://doi.org/10.1371/journal.pone.0251628 |
work_keys_str_mv |
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