Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis

<p>Abstract</p> <p>Background</p> <p>Secreted protein acidic and rich in cysteine (SPARC), a calcium-binding matricellular glycoprotein, is implicated in the progressions of some cancers. However, no information has been available to date regarding the function of SPARC...

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Bibliographic Details
Main Authors: Chen Jie, Shi Dehuan, Liu Xiaoyan, Fang Shuang, Zhang Jie, Zhao Yueran
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Subjects:
SPARC
Cervical cancer
Proliferation
Apoptosis
Metastasis
Online Access:http://www.biomedcentral.com/1471-2407/12/464

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