PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations
<b>Background:</b> Ovarian cancer is the 7th most common cancer and 8th most mortal cancer among woman. The standard treatment includes cytoreduction surgery followed by chemotherapy. Unfortunately, in most cases, after treatment, cancer develops drug resistance. Decreased expression and...
Main Authors: | Monika Świerczewska, Karolina Sterzyńska, Karolina Wojtowicz, Dominika Kaźmierczak, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/8/2053 |
Similar Items
-
Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development
by: Karolina Sterzyńska, et al.
Published: (2018-12-01) -
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer
by: Ling-Shih Chang, et al.
Published: (2020-01-01) -
Piperine Targets Different Drug Resistance Mechanisms in Human Ovarian Cancer Cell Lines Leading to Increased Sensitivity to Cytotoxic Drugs
by: Karolina Wojtowicz, et al.
Published: (2021-04-01) -
Inhibiting effect of ginsenoside Rh2 in vitro on nasopharynx cancer CSCs proliferation
by: Yong Liu
Published: (2016-08-01) -
MiRNA-mediated EMT and CSCs in cancer chemoresistance
by: Bing Dong, et al.
Published: (2021-02-01)